These cartridges are pretty easy to use. Since they are large, you don't have to refill them as often as the regular cartridges. They protrude outside of your printer and require you to install an AIR FILTER where the AIR VENT hole is located (refer to the pictures below for a better explanation). You can try to use these in conjunction with your original Brother cartridges, but we would recommend to use all of our cartridges as a set. Hope this helps! E-mail us (firstname.lastname@example.org
) if you have any other questions or concerns!