There should be one of two things on top of your refillable cartridges: (1) Two plugs or (2) One plug and a piece of tape. How the cartridges work is that there is an air vent on top of your cartridges that allow air to travel through, thus allowing ink to flow through and print onto your pages. You would have to either remove one of the plugs or the piece to tape to 'expose' the air vent. You should be able to print after you remove it. When you need to refill the cartridges, you would have to take the cartridges out of your printer, remove the refill plug and insert ink through that hole.
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CisInks Customer Service Team